contact cv about

kartik pradeepan

kartikspradeepan@gmail.com | +1 (647) 999 5698 | in/KartikPradeepan

Computational neuroscientist with 6 years of experience developing analytical tools and interpretive models seeking to leverage my experience to inform business decisions and build data products.



Education

PhD, Neuroscience @ Western University (Sept 2018 - Present)

BSc, Honours Double Major in Genetics and Physiology @ Western University (Sept 2013 - April 2018)

Select Awards

NSERC Postgraduate Scholarship - Doctoral (PGS-D), $63,000 CAD

Awarded for the project investigating multiscale comparisons of stem cell- derived neuronal networks to understand gene-related autism spectrum disorder. Project and expertise ranked in the top 90th percentile of applicants.

Ontario Graduate Scholarship (OGS), $15,000 CAD (Declined)

Awarded to graduate students in Ontario based on merit. Declined due to acceptance of NSERC PGS-D award.

Axion Travel Award, $1000 USD

2. Awarded $500 USD for work titled “Modeling from single cell electrophysiology to neuronal network interactions in human stem cell derived Rett Syndrome” which was presented as a talk at the Gordon Research Conference 2022 in Barga, Italy.

1. Awarded $500 USD for work titled “Developmental population-level differences in iPSC-derived excitatory networks of SHANK2 ASD” which was presented as a talk at the Society for Neuroscience Annual Meeting 2019 in Chicago, US.

Thales Student Innovation Case Competition Grand Prize, $20,000 CAD

Problem: Design an AI capable of automatically finding opinion clusters and analyzing a piece of evidence.

Solution: "Opinion Galaxies: A Machine Learning Network Approach to Big Data in Medical Research." An algorithm that creates an interactive multidimensional network of research, where papers are connected based on similarity in views and opinions based off of natural language processing.

Academic Work Experience

Human Physiology 2130 (Sept 2022 - May 2023)

Graduate Teaching Assistant to 300 students.

Instructed by Dr. Pierre Thibeault.

Human Physiology 2130 (Sept 2021 - May 2022)

Graduate Teaching Assistant to 900 students.

Instructed by Dr. Christine Bell.

Human Physiology 3120 (Sept 2020 - May 2021)

Graduate Teaching Assistant to 350 students.

Instructed by Prof. Tom Stavraky.

Physiology of Senses 4710 (Sept 2019 - Jan 2020)

Graduate Teaching Assistant to 140 students.

Instructed by Dr. Tutis Villis.

Kramer Lab (Jan 2016 - May 2018)

Research Assistant

Investigated the role of epigenetic regulation in learning and memory in the context of intellectual disabilities.

Research project: "Primer design and optimizing gene knockdown using qPCR in drosophila transgenic RNAi lines."

Research Contributions

Manuscripts Submitted to a Refereed Journal

4. Distinct neural codes in primate hippocampus and lateral prefrontal cortex during associative learning in virtual environments. Corrigan BW, Gulli RA, Doucet G, Roussy M, Luna R, Pradeepan KS, Sachs AJ, Martinez-Trujillo J (2022). Neuron.

3. Multielectrode Arrays for Functional Phenotyping of Neurons from Induced Pluripotent Stem Cell Models of Neurodevelopmental Disorders. McCready FP, Gordillo-Sampedro S, Pradeepan KS, Martinez-Trujillo J, Ellis J. (2022). Biology.

2. Wide spectrum of neuronal and network phenotypes in human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations. Mok RSF, Zhang W, Sheikh TI, Pradeepan KS, Fernandes IR, DeJong LC, Benigno G, Hildebrandt MR, Mufteev M, Rodrigues DC, Wei W, Piekna A, Liu J, Muotri AR, Vincent JB, Muller L, Martinez-Trujillo J, Salter MW, Ellis J. (2021). bioRxiv.

1. Present state of brain machine interfaces. Pradeepan KS (2019). Health Science Inquiry 2019.

Conferences and Presentations

International

6. Emergence of reverberating bursts in human stem cell derived neuronal networks of Rett Syndrome. Pradeepan KS*, Mok RF, McCready FP, Zhang W, Salter MW, Ellis J, Muller L, Martinez-Trujillo J. (2022). Society for Neuroscience Annual Meeting (Poster).

5. Modeling from single cell electrophysiology to neuronal network interactions in human induced pluripotent stem cell derived Rett Syndrome and isogenic controls. Pradeepan KS*, Benigno G, Zhang W, Mok RF, Martinez-Trujillo J, Muller L, Salter M, Ellis J. (2022). Gordon Research Conference for Fragile X and Autism-Related Disorders (Poster).

5. Modeling from single cell electrophysiology to neuronal network interactions in human induced pluripotent stem cell derived Rett Syndrome and isogenic controls. Pradeepan KS*, Benigno G, Zhang W, Mok RF, Martinez-Trujillo J, Muller L, Salter M, Ellis J. (2022). Gordon Research Seminar for Fragile X and Autism-Related Disorders (Talk).

4. Computational modeling of iPSC-derived Rett Syndrome Neuronal Networks. Pradeepan KS*, Benigno G, Mok RF, Martinez-Trujillo J, Muller L, Ellis J. (2021). Society for Neuroscience Annual Meeting (Poster).

3. Electrophysiological characterization of Rett Syndrome in iPSC-derived neuronal networks using computational network modeling. Pradeepan KS*, Benigno G, Mok RF, Martinez-Trujillo J, Muller L, Ellis J. (2021). Canadian Association for Neuroscience Annual Meeting (Poster).

2. Developmental population-level differences in iPSC-derived excitatory networks of SHANK2 ASD. Pradeepan KS*, McCready FP, Martinez-Trujillo J, Muller L, Salter M, Ellis J. (2019). Society for Neuroscience Annual Meeting (Dynamic Poster).

1. Electrophysiological characterization and neuronal network modelling of Rett Syndrome in iPSC-derived neuronal networks. Pradeepan KS*, Khaki M, Mok RF, Ellis J, Martinez-Trujillo J. (2019). Canadian Association for Neuroscience Annual Meeting (Poster).

Regional

2. Electrophysiological characterization and neuronal network modelling of Rett Syndrome in iPSC-derived neuronal networks. Pradeepan KS*, Mok RF, Ellis J, Muller L, Martinez-Trujillo J. (2021). London Health Research Day (Poster).

1. Making neurons to study autism. Pradeepan KS*. (2019). Kiwanis Senior's Center (Talk).

Institutional

9. Emergence of reverberating bursts in human stem cell derived neuronal networks of Rett Syndrome. Pradeepan KS*, Mok RF, McCready FP, Zhang W, Salter MW, Ellis J, Muller L, Martinez-Trujillo J. (2022). Schulich School of Medicine and Dentistry Neuroscience Seminar (Talk).

8. Modeling from single cell electrophysiology to neuronal network interactions in human induced pluripotent stem cell derived Rett Syndrome and isogenic controls. Pradeepan KS*, Benigno G, Zhang W, Mok RF, Martinez-Trujillo J, Muller L, Salter M, Ellis J. (2022). Developmental Disabilities Research Day (Talk).

7. Electrophysiological differences in patient-derived Rett Syndrome model. Pradeepan KS, Martinez-Trujillo J*. (2022). Schulich School of Medicine and Dentistry Psychiatry Grand Rounds (Talk).

6. Electrophysiological characterization of human stem cell derived networks of excitatory neurons in Rett Syndrome. Pradeepan KS, Benigno G, Muller L, Martinez-Trujillo J*. (2020). Developmental Disabilities Research Day (Talk).

5. Analyzing the electrophysiological effects of Rett Syndrome on neuronal network development using machine learning. Pradeepan KS*, Khaki M, Mok, RF, Martinez-Trujillo J, Ellis J. (2019). Developmental Disabilities Research Day (Poster).

4. Analyzing the electrophysiological effects of Rett Syndrome on neuronal network development using machine learning. Pradeepan KS*, Khaki M, Mok, RF, Martinez-Trujillo J, Ellis J. (2019). Clinical Neurological Research Day (Poster).

3. Analyzing the electrophysiological effects of Rett Syndrome on neuronal network development using machine learning. Pradeepan KS*, Khaki M, Mok, RF, Martinez-Trujillo J, Ellis J. (2019). Neuroscience Research Day (Poster).

2. Population analysis for the development of iPSC-derived glutamatergic networks. Pradeepan KS*, Mok RF, Martinez-Trujillo J, Ellis J. (2019). Robarts Research Institute Data Club (Talk).

1. Inspiration from the brain: modeling neuron network development. Pradeepan KS*. (2019). 3-Minute Thesis (Talk).

Activities

Scientific Outreach and Public Communication
Society of Neuroscience Graduate Students Dorsal Column Writer Sept 2019 - Present
Society of Neuroscience Graduate Students Outreach Team Sept 2019 - Present
Society of Neuroscience Graduate Students Presentation Workshop Committee Sept 2019 - Present
Incomplete Thoughts Podcast Host Sept 2019 - Present
Simply Neuroscience - Synaptic Hacks 2021 Interdisciplinary neuroscience hackathon July 2021 - Aug 2021
Science Rendezvous Neuroscience Organizer Feb 2021 - May 2022
Let's Talk Science Jan 2019 - Aug 2020
Society of Neuroscience Graduate Students Mentorship Committee Member Jan 2019 - Aug 2020
Gradcast #240 Podcast - "Making Neurons to Study Autism" Oct 2019
Thames Valley Science & Engineering Fair Apr 2019
Retiring with Strong Minds presentation - Kiwanis Senior's Center Mar 2019
Be Al U CaN B Genetics in-class (grade 7/8) presentation - Mr. Gardiner At Abdereen PS Feb 2019
Clickbait Medicine Podcast #2 - Cognitive Behavioural Therapy Jan 2019
Leadership and Organization
Society of Graduate Students Neuroscience Councillor Sept 2020 - Sept 2022
Society of Neuroscience Graduate Students Presentation Workshop Chair July 2020 - May 2022
University Consulting Group Consultant (Jan 2022 - May 2022) & Team Lead Sept 2022 - Dec 2022
Robarts Association of Trainees and Students Council May 2019 - June 2021

Projects

Human Stem Cell Database for Neurodevelopmental Disorders [in development]

Will be the first open access human neurophysiology database for the dissemination of intracellular and extracellular electrophysiological data related to various neurodevelopmental disorders.

Agile development environment.

Primate Cell Type Database [prototype]

An open access database for intracellular electrophysiological and morphological data obtained from non-human primates sampled from the lateral prefrontal cortex.

Conceptualized and developed the functioning prototype for a large, multi-national research grant (NSF Neuronex).

Agile development environment.

Relevant Academic Courses

Computer Science

Biomedical Applications of Neural Networks, Introduction to Neural Networks, Data Science for the Life Sciences, Programming for the Life Sciences

Medical Sciences

Advanced Genetics, Cellular Physiology, Homeostasis and Stress, Healthcare Law, Cellular and Molecular Neurobiology, DNA: Genome Organization, Mutagenesis & Repair, Developmental Biology, Human Molecular Biology, Human Physiology, Motor Neurophysiology, Organogenesis in Mammals, Physiology of Stem Cell Function, Physiology of the Senses, Principles of Human Genetics, Regulation of Gene Expression, Skeletal Health and Disease

Technical Skills

Programming Languages: Python (/Jupyter Notebook), Matlab, SQL, bash, git
ML/AI: Scipy, Numpy, Pandas, Scikit-learn, Pytorch, Tensorflow, Keras, Statsmodel, Nevergrad, Unidip
Natural Language Processing: SpaCy (word2vec), NTLK (VADER), Topic Modeling (LDA/ NMF), Text Generation (LSTM)
Visualization: Matplotlib, Seaborn